Phthalic acid and derivatives
Apexbio Technology LLC Cyclic Pifithrin-α hydrobromide 511296-88-1 10mg
Cyclic Pifithrin- hydrobromide (CAS 511296-88-1) is a synthetic small molecule that functions as an inhibitor of the tumor suppressor protein p53 By blocking p53-dependent transcriptional activation of response genes it interferes with p53-mediated cellular processes such as apoptosis and cell cycle arrest In vitro Cyclic Pifithrin- hydrobromide inhibits p53-dependent apoptosis and DNA damage-induced growth arrest in various cell models without notable effects on p53-deficient cells In vivo it protects mice from the toxic side effects of genotoxic cancer therapies likely through suppression of p53-dependent pathways This compound is utilized in research investigating p53 biology cellular stress responses and modulation of chemotherapeutic toxicity
eMolecules 1679-64-7 | mono-Methyl terephthalate | Chem-Impex | MFCD00002557 | 180.159 | C9H8O4 | 99.000 | COC(=O)c1ccc(cc1)C(O)=O | 5g | 386903715
mono-Methyl terephthalate | Chem-Impex | 1679-64-7 | MFCD00002557 | 180.159 | C9H8O4 | 99.000 | COC(=O)c1ccc(cc1)C(O)=O | 5g | 386903715
Medchemexpress LLC Cyclic AMP-13C5 (Cyclic adenosine monophosphate-13C5) | 2170095-23-3 | 97.5% | 1 MG
Cyclic AMP-13C5 is a deuterated cyclic AMP. This compound can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Contains stable heavy isotopes.
Medchemexpress LLC Cyclic AMP sodium | 37839-81-9 | 99.97% | 250 MG
Cyclic AMP (Cyclic adenosine monophosphate) sodium, an adenosine triphosphate derivative, is an intracellular signaling molecule that directs cellular responses to extracellular signals. It acts as an important second messenger in many biological processes. It also modulates mediator generation, suppressing the expression of pro-inflammatory cytokines and enhancing the production of anti-inflammatory cytokine.
- Acts as an important second messenger
- Modulates mediator generation
- Suppresses pro-inflammatory cytokines like TNF-α and IL-12
- Enhances anti-inflammatory cytokine IL-10 production
TARGETMOL CHEMICALS INC BAY 61-3606 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. BAY 61-3606 (Syk inhibitor IV) is a potent ATP-competitive reversible and highly selective inhibitor of Syk tyrosine kinase activity (Ki= 7.5 nM) exhibiting no inhibitory effect against Btk Fyn Itk Lyn and Src. purity: 98%
Medchemexpress LLC Cyclic GMP (Standard) | 7665-99-8 | 99.5% | 345.21 | 25 MG
Cyclic GMP (Standard) | 7665-99-8 | 99.5% | 345.21 | 25 MG
Medchemexpress LLC EDTA (disodium) | 139-33-3 | MFCD00070672 | 98.0% | 336.21 g/mol | C10H14N2Na2O8 | 10 G
EDTA disodium (ethylenediaminetetraacetic acid disodium salt) is a water-soluble chelating agent that sequesters divalent and trivalent metal ions. It is commonly used in biochemical, analytical, and formulation applications to control metal-catalyzed reactions, stabilize solutions, and improve product shelf life. The material is provided in small research pack sizes with a reported purity of 98.0%.
- Water-soluble chelating agent for sequestering metal ions.
- Helps prevent metal-catalyzed oxidation and degradation in formulations.
- Suitable for buffer preparation and analytical methods.
- Reported purity 98.0% for general laboratory use.
- Available in small research pack sizes for convenience.
Medchemexpress LLC Sulbenicillin disodium | 28002-18-8 | 50 MG
Sulbenicillin disodium is the disodium salt of Sulbenicillin. Sulbenicillin is a Penicillin antibiotic that exhibits antibacterial activity against various mucoid and non-mucoid strains of Pseudomonas aeruginosa.
- Purity: 98.84%
- Molecular Weight: 458.42
- Formula: C16H16N2Na2O7S2
- Appearance: Solid
- Color: White to off-white
- Storage: 4°C, sealed storage, away from moisture
- In-solvent storage: -80°C for 6 months or -20°C for 1 month, sealed and away from moisture
- Solubility in H2O: 250 mg/mL (requires sonication)
- Solubility in PBS: 100 mg/mL (clear solution; requires sonication)
eMolecules 28179-47-7 | MONOMETHYL-5-AMINO-ISOPHTHALATE | AstaTech | MFCD00224870 | 195.174 | C9H9NO4 | 95.000 | COC(=O)c1cc(N)cc(c1)C(O)=O | 5g | 233616389
MONOMETHYL-5-AMINO-ISOPHTHALATE | AstaTech | 28179-47-7 | MFCD00224870 | 195.174 | C9H9NO4 | 95.000 | COC(=O)c1cc(N)cc(c1)C(O)=O | 5g | 233616389
Medchemexpress LLC 8-CPT-Cyclic AMP sodium | 93882-12-3 | 99.7% | 493.79 | 10 MG
8-CPT-Cyclic AMP sodium is a selective activator of cyclic AMP-dependent protein kinase (PKA). It is also a potent inhibitor of the cyclic GMP-specific phosphodiesterase (PDE VA) with an IC50 of 0.9 μM. Additionally, 8-CPT-Cyclic AMP sodium inhibits PDE III and PDE IV with IC50 values of 5.5 μM and 6.6 μM, respectively, and is a potent Epac activator. It has been shown to delay TNF-α/CHX-induced and α-Fas-induced apoptosis in neutrophils.
- Selective activator of cyclic AMP-dependent protein kinase (PKA).
- Potent inhibitor of cyclic GMP-specific phosphodiesterase (PDE VA) with an IC50 of 0.9 μM.
- Inhibits PDE III and PDE IV with IC50 values of 5.5 μM and 6.6 μM.
- Potent Epac activator.
- Delays TNF-α/CHX-induced and α-Fas-induced apoptosis in neutrophils.
Medchemexpress LLC Disodium 5'-inosinate | 4691-65-0 | 99.7% | 25 G
Disodium 5'-inosinate is a nucleotide-based umami agent. It can bind to umami receptors and stimulate taste nerves, allowing the brain to perceive umami. In addition, it produces a transient behavioral excitement in mice.
- Responds to oral stimulation in rat solitary-tract nucleus neurons, involved in encoding umami taste.
- Produces transient behavioral excitement in mice.
- In mice (500 mg/kg, intravenous injection), it led to increased movement, jumping, squeaking, enhanced preening, and increased reflex response, with sedation after 60 minutes.
Medchemexpress LLC Terephthalic acid | 100-21-0 | 99.99% | 166.13 | 100 MG
Terephthalic acid is an isomer and precursor of polyester PET, widely used in textiles and plastics. It is also utilized in biological research for developing skin tumor models. This compound promotes cell proliferation and can induce skin tumor formation by interfering with the p16-cyclin D1/Cdk4-Rb cell cycle regulatory pathway.
- Isomer and precursor of polyester PET
- Used in clothing and plastics
- Can be used to build skin tumor models
- Promotes excessive cell proliferation
- Induces skin tumor formation
- May lead to bladder stone formation at higher doses
Medchemexpress LLC Carbenoxolone disodium | 7421-40-1 | MFCD03840711 | 99.9% | 25 MG
Carbenoxolone disodium is the active metabolite of Glycyrrhizic acid and an inhibitor of human 11β-HSD and bacterial 3α, 20β-HSD. It functions as an uncoupling agent for gap junctions and is a potent inhibitor of Vaccinia virus replication. This product is used for research into peptic, esophageal, and oral ulceration and inflammation.
- Active metabolite of Glycyrrhizic acid.
- Inhibitor of human 11β-HSD and bacterial 3α, 20β-HSD.
- Uncoupling agent for gap junctions.
- Inhibitor of Vaccinia virus replication.
- Used for studying peptic, esophageal, and oral ulceration and inflammation.